Publication by our Team Members

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White Paper: The critical role of understanding chronic inflammation

The importance of novel inflammatory biomarkers immune profiling in prediction of coronavirus disease severity.

2020-06-16T19:48:06-07:00April 25th, 2020|Publication by our Team Members|

Chronic inflammation in the etiology of disease across the life span

In the present Perspective we describe the multi-level mechanisms underlying SCI and several risk factors that promote this health-damaging phenotype, including infections, physical inactivity, poor diet, environmental and industrial toxicants and psychological stress.

2020-06-16T19:51:29-07:00December 12th, 2019|Publication by our Team Members|

Multicenter Systems Analysis of Human Blood Reveals Immature Neutrophils in Males and During Pregnancy

Despite clear differences in immune system responses and in the prevalence of autoimmune diseases between males and females, there is little understanding of the processes involved.

2020-06-16T19:52:38-07:00February 7th, 2017|Publication by our Team Members|

Expression of specific inflammasome gene modules stratifies older individuals into two extreme clinical and immunological states

Low-grade chronic inflammation has been associated with many of the diseases associated with aging, but the mechanisms that produce this inflammation are poorly understood.

2020-06-16T19:53:41-07:00January 16th, 2017|Publication by our Team Members|

Defective Signaling in the JAK-STAT Pathway Tracks with Chronic Inflammation and Cardiovascular Risk in Aging Humans

A longitudinal study reveals in older adults systemically reduced immune cell signaling responses that are stable at least 3 years and are predictive of cardiovascular disease.

2020-06-16T19:54:40-07:00October 26th, 2016|Publication by our Team Members|

Cytomegalovirus infection enhances the immune response to influenza

Cytomegalovirus (CMV) is a b-herpesvirus present in a latent form in most people worldwide. In immunosuppressed individuals, CMV can reactivate and cause serious clinical complications, but the effect of the latent state on healthy people remains elusive.

2020-06-16T19:56:48-07:00April 1st, 2015|Publication by our Team Members|

Systems analysis of sex differences reveals an immunosuppressive role for testosterone in the response to influenza vaccination

There are marked differences between the sexes in their immune response to infections and vaccination, with females often having significantly higher responses.

2020-06-16T14:21:27-07:00January 14th, 2014|Publication by our Team Members|