Markers of the systemic inflammatory response, including C-reactive protein and albumin, as well as neutrophil, lymphocyte and platelet counts have been shown to be prognostic of survival in patients with cancer. The aim of the present study was to examine the prognostic relationship between these markers of the systemic inflammatory response and all-cause, cancer, cardiovascular and cerebrovascular mortality in a large incidentally sampled cohort.
While modernization has dramatically increased lifespan, it has also witnessed the increasing prevalence of diseases such as obesity, hypertension, and type 2 diabetes. Such chronic, acquired diseases result when normal physiologic control goes awry and may thus be viewed as failures of homeostasis.
Systems analysis of sex differences reveals an immunosuppressive role for testosterone in the response to influenza vaccination
There are marked differences between the sexes in their immune response to infections and vaccination, with females often having significantly higher responses.
It is now recognized that a mild pro‐inflammatory state is correlated with the major degenerative diseases of the elderly.
Inflammation is classically recognized as an essential step for the control of microbial invasion or tissue injury as well as for the maintenance of tissue homeostasis under a variety of noxious conditions.